Gabapentinoids & Antiepileptics: Core Concepts

Course Description:
This course is part of our Core Concepts Series, which reviews potentially impairing drug classes from three scientific perspectives: Pharmacology, Forensic Toxicology, and Clinical Toxicology. A future supplemental series will add law enforcement and DRE perspectives for each drug class as well.

Gabapentinoids and antiepileptics, while primarily used to treat neurological conditions like epilepsy and neuropathic pain, have diverse usage profiles and share notable similarities in their mechanisms and impact on the central nervous system. Moreover, these drugs are often used in combination with other medications and can contribute to a variety of drug-drug interactions – including additive effects on cognitive and motor skills.

The prevalence of these medications and complexity of their interactions with other potentially impairing drugs makes a thorough understanding of their pharmacology and toxicology critical to forensic practice – from the roadside, to the lab, to the courtroom.
Recommended Learners:
Toxicologist
DRE
LEO
gabapentin anti epileptics anticonvulsants cover
Dr. Michelle Peace

Dr. Michelle Peace

Dr. Peace is a forensic toxicologist and a Full Professor in the FEPAC-accredited Department of Forensic Science at VCU and is one of the founding faculty for the Department. She served as Associate Chair and Chair for nearly a decade. See full bio. 

Kristen Burke, MBA

Kristen Burke, MBA

Kristen retired from public service in 2022 and worked in the Toxicology field for over 24 years. She is a Toxicology Liaison for the National Highway Traffic Safety Administration Region 9 and supports AZ, CA, HI, and Pacific Territories. See full bio. 

Dr. Dayne Laskey

Dr. Dayne Laskey

Dr. Laskey is an associate professor at the University of Saint Joseph in West Hartford, CT. He received a PharmD from the University of Connecticut, completed his pharmacy practice residency at Grady Memorial Hospital in Atlanta, and his clinical toxicology fellowship from the Georgia Poison Center. See full bio. 

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Gabapentinoids & Antiepileptics: Core Concepts

Course Description:
This course is part of our Core Concepts Series, which reviews potentially impairing drug classes from three scientific perspectives: Pharmacology, Forensic Toxicology, and Clinical Toxicology. A future supplemental series will add law enforcement and DRE perspectives for each drug class as well.

Gabapentinoids and antiepileptics, while primarily used to treat neurological conditions like epilepsy and neuropathic pain, have diverse usage profiles and share notable similarities in their mechanisms and impact on the central nervous system. Moreover, these drugs are often used in combination with other medications and can contribute to a variety of drug-drug interactions – including additive effects on cognitive and motor skills.

The prevalence of these medications and complexity of their interactions with other potentially impairing drugs makes a thorough understanding of their pharmacology and toxicology critical to forensic practice – from the roadside, to the lab, to the courtroom.
Recommended Learners:
Toxicologist
DRE
LEO
gabapentin anti epileptics anticonvulsants cover
Dr. Michelle Peace

Dr. Michelle Peace

Dr. Peace is a forensic toxicologist and a Full Professor in the FEPAC-accredited Department of Forensic Science at VCU and is one of the founding faculty for the Department. She served as Associate Chair and Chair for nearly a decade. See full bio. 

Kristen Burke, MBA

Kristen Burke, MBA

Kristen retired from public service in 2022 and worked in the Toxicology field for over 24 years. She is a Toxicology Liaison for the National Highway Traffic Safety Administration Region 9 and supports AZ, CA, HI, and Pacific Territories. See full bio. 

Dr. Dayne Laskey

Dr. Dayne Laskey

Dr. Laskey is an associate professor at the University of Saint Joseph in West Hartford, CT. He received a PharmD from the University of Connecticut, completed his pharmacy practice residency at Grady Memorial Hospital in Atlanta, and his clinical toxicology fellowship from the Georgia Poison Center. See full bio. 

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